Matthew Gage

Assistant Professor, Department of Chemistry and Biochemistry
Northern Arizona University
P.O. Box 5698
Flagstaff, AZ 86011-5698
matthew.gage@nau.edu
Phone: (928) 523-6394
http://jan.ucc.nau.edu/~mjg95

Research area in Robinson lab: Protein aggregation

 

Ozge Can

Assistant Professor, Department of Medical Biochemistry
School of Medicine
Acibadem University
Gulsuyu Mahallesi
Fevzi Cakmak Caddesi
Divan Sokak, No: 1
Maltepe, Insnabul
TURKEY
Phone: +90 (216) 4580874
OZGE.CAN@acibadem.edu.tr

Research area in Robinson Lab: Designing optimal systems for the expression and detection of functionally active human G-protein coupled receptors in yeast through protein engineering and random mutagenesis coupled with advanced techniques such as FACS (Fluorescence activated cell sorting) and multi-photon confocal microscopy

 

David Raden

Research area in Robinson lab: Stress response in yeast.

david@raden.us

Arash Foroutan

Research area in Robinson Lab: Purification and conformational characterization of adenosine A2b receptor, and Neurokinin 1 receptor. Study of structural transition and self assembly of proteins (e.g. Tau, gamma D Crystallin, alpha synuclein) Study and characterization of protein/small molecule inhibitors interactions

arfo58@gmail.com

Kory Blocker

Research area in Robinson Lab: Investigation of an engineered GPCR through random mutagenesis and GPCR expression in non-native environments by studying the ligand-binding response.

kory.blocker@gmail.com

Brian Lefebvre, May 2002

Thesis Title: “High Pressure Dissociates Tailspike Aggregates and Promotes Native Structure Formation”
Assistant Professor, Rowan University, NJ (2004-2008)
Current Position, Senior Research Engineer, DuPont & Co.
bglefebvre@yahoo.com

 

James Butz, June 2002

Thesis Title:“Characterizing and Optimizing GPCR Expression in Yeast”
Current position: Associate Principal Scientist, Respiratory Product Development, Merck Research Laboratories
james.butz@spcorp.com

 

Brenda Danek, March 2003

Thesis Title:“Characterization of the Role of Disulfides in Folding of Tailspike Protein”
J.D., 2008, New York University
Current Position: Associate, Leydig, Voit & Mayer, LLP

 

Jessica Sinacola, August, 2003

Thesis Title:“Characterization and Reversal of the Aggregation of Single-Chain Antibodies”
Current position: Process Engineer, Sterile Process Technology & Engineering, Merck & Co, West Point, PA.
jessica_sinacola@merck.com

 

Jason Smith, July 2003

Thesis Title:“Folding and Expression of Extremophilic Enzymes”
Current position: Manager of Research and Development, Carmell Therapeutics, Pittsburgh, PA.
jasonsmith504@gmail.com

 

Ronald Niebauer, July 2005

Thesis Title:“Using GFP as a Sensor for Optimizing Expression of GPCRs”
Current position: Biotechnology Patent Examiner, US Patent Office, Washington, DC.
ronaldniebauer@hotmail.com

 

Junghwa Kim, June 2006

Thesis Title:“Roles of Folding Intermediate Conformation and Transient Disulfide Bonding on the Folding of P22 Tailspike Protein”
Current position: Scientist, MedImmune

 

Sara Lawrence Powers, July 2006

Thesis Title:“Characterization and Expression of an Extremely Stable Hyperthermophilic Protein”
Current position: Biomatrica.
saralpowers@gmail.com

 

Ping Xu, July 2006

Thesis Title:“Sensing and Analyzing the Unfolded Protein Response during Heterologous Protein Production”
Current position: Scientist, Glaxco Smith Kline

 

Steven Bane, May 2007

Thesis Title:“Expression and Characterization of the Human Neurokinin 1 receptor from E. coli”
Current position: Scientist, Amgen

 

Emily McCusker, December 2007

Thesis Title:“Overcoming Expression Obstacles in Producing Functional Components of the G-Protein Coupled Receptor Pathway”
Current position: Teva Pharmaceuticals
e.mccusker@mail.cryst.bbk.ac.uk

 

Michelle L. Spatara, August, 2009

Thesis Title:"Protein folding and aggregation: in vitro and in vivo"
Current position: Investigator, GSK

 

Michelle O’Malley, August 2009

Thesis Title:“Expression, Purification, and Biophysical Characterization of G-Protein
Coupled Receptors Expressed from Saccharomyces cerevisiae”
Current position: Assistant Professor, Chemical Engineering, UC Santa Barbara, website
momalley@engineering.ucsb.edu

Carissa Young, December 2012

Thesis Title:"Interrogation of Quality Control Mechanisms and Protein Trafficking in Saccharomyces cerevisiae"           
Current Position: Postdoctoral fellow, MIT          

Zachary Britton, December 2012

Thesis Title: “Novel Approaches to the Expression and Purification of G-Protein Coupled Receptors”
Current Position: Scientist, MedImmune

Melissa St. Amand, September 2013

Thesis Title: “Toward Online Quality Control during Biopharmaceutical Production”
Current Position: post-doctoral fellow, Biotechnology Core Lab., ODIR, NIDDK, NIH

Andrea Naranjo, October 2014

Thesis Title: “Stability and Activity of a GPCR in vivo and in Membrane Mimetic Environments”
Current Position: post-doctoral fellow, NIH

Patrick McNeely, July 2015

Thesis Title: “Receptor-receptor, Ligand, and Membrane Interactions of the Adenosine A2A Receptor”

Davesh Radakrishnan, October 2016

Thesis Title: “Modeling, Estimation, and Control of Glycosylation in Mabs Produced in CHO Cells”
Current Position: Scientist, Manufacturing Sciences, BioMarin Pharmaceuticals

Jonathan Dueber (BS, 1999, Chemistry & Biochemistry)

“Expression, purification and refolding of tailspike aggregates”
PhD, UC San Francisco, Dept of Biochemistry
Current Position: Assistant Professor, Department of Bioengineering, University of California, Berkeley and and Energy Biosciences Institute
jdueber@berkeley.edu

 

Alexander Harris (BS, 2000)

“The Role of Stress in Protein Expression in Yeast”
Sous-Chef at Le Caprice, New York City
zelkinor@hotmail.com

 

Eveline Tseng (BS, 2000)

“Analysis of the Interactions between human A2a and BiP"

 

Kathryn Whitehead (BS, 2002)

“Role of Additives in Preventing Aggregation of P22 Tailspike”
PhD, Chemical Engineering, UC Santa Barbara, NSF Graduate Fellow Honorable Mention
Current position: Postdoctoral fellow, Lab of Prof. Robert Langer, Koch Institute for Integrative Cancer Research, MIT
kawhite@mit.edu

 

Noelle Comolli (BS, 2003)

“Tsf Mutations Alter the Rate and Pathway for Tailspike Aggregation”
PhD, Chemical Engineering, Drexel University
Current Position: Assistant Professor, Department of Chemical Engineering, Villanova University
noelle.comolli@villanova.edu

 

Eric Pridgen (BS, 2003)

“Molecular Sensors for Detecting Cellular Stress”
Process Engineer for Merck for 3 years
Current Position: graduate student in Ph.D. program at MIT. NDSEG Department of Defense Graduate Fellow 2007-2010.
epridge@yahoo.com

 

Ben Tang (BS, 2003)

“Role of Chaperones in Extremophile Expression in Yeast”
Current position: graduate student in Ph.D. program at Johns Hopkins University.
btang@jhu.edu

 

Dana Ungerbuehler (BS, 2003)

“Cysteine Mutation Effects on Tailspike Folding”
MMDP Analyst, Merck Manufacturing Management Development Program for 2 years
Current Position: Medical Student at Rutgers Medical School.
danajoy29@yahoo.com

 

Jennifer Zak [Grey] (BS, 2003)

“Role of Salt Bridging in Trimer Assembly of Tailspike”
Process Engineer for Merck for 3 years
jennifer_grey@merck.com

 

Amy VanFossen (BS, 2004)

“Stress Response in GPCR Expression in Yeast”
PhD, Chemical Engineering, NC State University
Current Position: Biofuel researcher at Agrivida, Medford, MA
alvanfossen@gmail.com

 

Alison (Wedekind) Tisdale (BS, 2005)

“Optimization and Characterization of G-Protein Coupled Receptor Expression in Yeast”
M.S., Chemical Engineering at University of Minnesota
Current Position: Assistant Scientist in Dr. Gary Nelsestuen's lab, University of Minnesota
wede0028@umn.edu

 

Elizabeth Bell (BS, 2005)

“Sublocalization of the Chaperone BiP within the Endoplasmic Reticulum of Yeast Cells and its Role in Protein Expression”
2004 Barry M. Goldwater Award.
Current Position: Implementation Specialist, Agilent Technologies
elizabeth_bell@agilent.com

 

Elizabeth Oeffinger (BS, 2006)

“Tailspike Beta Helix Variants: Effects of Sequence on Aggregation Propensity”
MS, Chemical Engineering, Princeton University.
elizabeth.oeffinger@gmail.com

 

Dominic Mancini (BS, 2008)

“The unfolded protein response in G-protein coupled receptor expression in yeast”
dominicmancini@me.com

 

Lindsay Schmiedel (BS 2009)

“Analyzing Spatial Localization of Proteins of the Endoplasmic Reticulum in Budding Yeast, S. cerevisiae, during Cell Division”
Current Position: Associate Engineer, Technical Rotation Program, Merck & Co., Inc.
lcschmiedel@gmail.com

 

Carly Fleagle (BS 2009)

“Evaluating the unfolded protein response of Saccharomyces cerevisiae”
Current Position: graduate student, University of Colorado
carly.fleagle@gmail.com

 

Amy Chevalier (BS 2011)

"Effect of cysteine mutations on A2aR trafficking in HEK 293 cells"
Current Position: graduate student, Chemical and Biomolecular Engineering, University of Pennsylvania
amychev@seas.upenn.edu